Over 65% of GLP-1 patients discontinue treatment within the first year.
For payers and providers, that means billions spent on patients already on their way out.
GLP-1 Continuity Intelligence

You are already paying for patients
on their way out.
Nobody sees it early enough.

Billions leak annually through silent GLP-1 abandonment — invisible until claims data confirms it's too late. Preventra gives care coordinators, pharmacists, and population health teams a daily prioritized list of patients to reach before treatment fails.

30-Day Dropout Segment
High-risk population ~20% loss
Stable population <3% loss
65%
discontinue within
year one
Zero
system overhaul
required
Days
to live data
integration
Built For
Health Plans ACOs Employer Health Programs Specialty Pharmacies Integrated Delivery Networks Population Health Teams Value-Based Care Organizations
"By the time a missed refill shows up in claims data, the opportunity to retain that patient has already disappeared. The failure was visible weeks earlier — in pharmacy signals your clinical system never saw."

Preventra connects those signals early enough to stop the leakage — fitting into your existing workflows without a single system overhaul.

65%
of GLP-1 patients discontinue treatment within the first year
$50B+
in wasted pharmaceutical spend linked to preventable dropout
#1
predictor of GLP-1 discontinuation is provider and pharmacy refill reliability — not side effects, not medication cost
How Preventra Works

Find likely drop-off patients early enough to act.

Preventra fits directly into your existing care operations. Care coordinators start each day with a ranked outreach list. Pharmacists see refill-risk flags before gaps occur. Population health teams track adherence trends across the full GLP-1 population — without touching your EHR configuration.

1

Connect to your existing systems

Native HL7/FHIR connectors for Epic, Cerner, and Athena — plus pharmacy claims feeds. Live within days, not months.

2

Unify clinical and pharmacy signals

Preventra fuses real-time refill data with clinical records to surface dropout risk before it becomes visible in claims data.

3

Daily outreach worklists for your care teams

Every patient ranked by discontinuation risk. Plain-language reason summaries. Recommended next action — call, pharmacist consult, financial assistance, or routine follow-up. No black-box scoring. No complex interpretation.

4

Measure financial impact in real time

Track avoidable pharmaceutical spend, intervention ROI, and shared savings impact across the full GLP-1 population. Financial and operational leadership see exactly where outreach produces measurable return — and where it does not.

Patient Risk Worklist
PatientRisk DriverAction
M. Torres
Refill gap · Day 22
High 94%
Call today
D. Nguyen
Provider change · Side effects
High 88%
Pharmacist consult
R. Okafor
Cost pressure · Income gap
Med 71%
Financial assist.
S. Kim
Pharmacy reliability
Med 65%
Pharmacy switch
L. Patel
Stable · On track
Low 18%
Routine follow-up
Preventra Insight
3 high-risk patients share a single pharmacy. Switching to a higher-reliability dispenser reduces projected dropout by 34% in this cohort.
Intelligence Architecture

Three pillars of GLP-1 continuity intelligence

Preventra's three modules address the full lifecycle of GLP-1 adherence risk — from the first care transition to refill gaps to the systemic pharmacy failures most platforms never surface.

Transitional Outcome Intelligence

Monitors care transitions and discharge patterns to identify patients at elevated dropout risk during the highest-vulnerability windows — the first 30 and 90 days of therapy.

Drug & Treatment Intelligence

Combines pharmacy refill data with clinical signals to predict medication adherence failures before they occur — revealing which patients need outreach today, not after the next claim.

Disruption Intelligence

Detects systemic breakdowns in provider and pharmacy reliability — the #1 predictor of GLP-1 failure — and flags population-level disruption before it cascades into widespread dropout.

Your existing tools are tracking adherence after failure has already begun.

Most organizations already have forecasting, population health dashboards, and EHR analytics. The problem isn't the absence of data — it's that every existing system surfaces GLP-1 dropout too late to act on it.

Refill Visibility

Claims data lags by 30–60 days

By the time a missed refill appears in your claims feed, the patient has already been off therapy for weeks. The intervention window is gone.

Data Fragmentation

Pharmacy and clinical data never connect

EHRs track clinical visits. PBMs track fills. Neither system sees the full picture. The dropout signal lives in the gap between them — where no existing tool looks.

Reactive Outreach

Care teams respond — they don't anticipate

Without early signals, outreach is triggered by events that have already happened. Care coordinators are managing dropout, not preventing it.

No Prioritization

Blanket outreach wastes limited capacity

Without ranked risk visibility, care teams contact everyone — or no one. High-risk patients get the same attention as stable ones. Resources scatter instead of focusing where they change outcomes.

Preventra closes this gap. By fusing real-time pharmacy refill signals with clinical data, it surfaces dropout risk days or weeks before any existing system — giving care teams a ranked worklist while intervention is still possible.

From missed refill to retained patient — in one coordinated workflow.

Here is exactly how Preventra fits into your care team's daily operations — no new systems, no retraining, no disruption.

01

Patient enters GLP-1 refill risk window

Preventra detects a combination of pharmacy refill timing, provider reliability signals, and clinical context — 14 to 30 days before a fill is actually missed.

02

Discontinuation risk flagged and ranked

The patient appears on the daily worklist, ranked by dropout probability. The reason is explained in plain language — financial pressure, pharmacy reliability gap, provider change, or side-effect pattern.

03

Care coordinator receives prioritized alert

The care coordinator — or pharmacist, or population health manager — sees the patient at the top of their list with a recommended action already generated. No interpretation required.

04

Outreach initiated before therapy abandonment

A targeted call, financial assistance referral, or pharmacy switch is initiated while the patient is still on therapy. The intervention window is open — because Preventra identified the risk early enough to use it.

Patient remains adherent. Spend protected.

Treatment continues. Shared savings are protected. The intervention cost is a fraction of the pharmaceutical spend that would have been wasted — and the outcome deterioration that would have followed.

Fits your operations today — no overhaul required

Preventra is not an EHR replacement. It is not a forecasting competitor. It is the operational coordination layer that connects pharmacy and clinical data, then surfaces the right intervention to the right care team member at the right moment — using systems you already have.

Epic
Cerner
Athena
HL7 / FHIR
Pharmacy PBM
Claims Feeds

No rip-and-replace. No implementation burden.

Preventra is an operational layer on top of your existing EHR, pharmacy, and analytics infrastructure. No new system for IT to manage. No staff retraining. No workflow disruption. Live within days.

Transparent, explainable risk flags

Every adherence risk flag includes ranked clinical and pharmacy drivers with a plain-language explanation. Care coordinators know exactly why a patient was flagged and what action to take — no data science interpretation required.

HIPAA-compliant by design

End-to-end encryption, role-based access controls, and full audit logging — meeting the security requirements of health systems, insurers, and ACOs out of the box.

Precision resource allocation

Preventra also identifies where intervention does not produce measurable return — so care teams allocate capacity to the patients where outreach actually changes outcomes. Precision resource use, not blanket outreach.

Retention failure is not random. It follows a pattern.

Preventra's retention analysis reveals not just which patient cohorts discontinue — but when, and why. Different failure patterns require different intervention strategies, timed to the right moment in each patient's treatment arc. Blanket outreach wastes resources. Timed, targeted intervention retains patients.

High-risk cohort — loses ~20% of patients in the first 30 days. Driven by provider and pharmacy reliability failures.
Cost-pressure cohort — gradual attrition tied to income-relative financial burden. Responds to assistance navigation outreach.
Stable cohort — remarkably consistent across six months. Different behavioral profile; different resource allocation.
Day 0 Day 30 Day 90 Day 150 Day 180 100% 75% 50% 25%
GLP-1 Treatment Retention — 180-Day Cohort Comparison
Financial Impact

Translate adherence risk into financial impact

Projected Net Annual Savings
$4.2M
after intervention costs
Patients retained 325
Gross drug spend protected $3.9M
Intervention program cost −$163K
Net annual ROI 24x

Estimates based on published GLP-1 adherence literature and Preventra population analytics benchmarks. Results vary by organization.

Executive Insight
"The financial risk begins long before the patient officially discontinues treatment. By the time missed adherence appears in traditional reporting workflows, the intervention window is often already closing. The organizations that will win in value-based care are the ones that see it coming — and act while there is still time."
— Preventra Platform Vision
Who Preventra Serves

Operational intelligence for every team managing GLP-1 continuity

Insurers & Health Plans

Stop paying for treatment patients have already abandoned.

GLP-1 adherence leakage is one of the fastest-growing sources of avoidable pharmaceutical spend. Preventra gives plans real-time visibility into which members are silently abandoning treatment — before it shows up in claims, when intervention is still possible.

ACOs & Value-Based Care

Protect shared savings before drop-off becomes a quality event.

Daily prioritized outreach lists align directly with MSSP and value-based contract performance. Population health and care coordination teams act before adherence failure becomes a quality measure miss or a readmission.

Integrated Health Systems

Give care coordinators and pharmacists the visibility to intervene earlier.

Connects pharmacy refill signals with clinical records across the enterprise — giving care coordinators daily worklists, pharmacists refill-risk flags, and CFOs a clear view of avoidable spend before it hits the books.

See which of your GLP-1 patients are already at risk.

Request a 30-minute operational walkthrough. We'll map Preventra's daily outreach workflow against your current care coordination process — and show you exactly where adherence risk is hiding in your population today.

Beginning with GLP-1 populations — with a roadmap built for oncology, cardiovascular, and specialty pharmacy.

Request a Demo Contact Sales